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College of Arts & Sciences
Department of Biological Sciences


Graduate Student Directory

Kimberly Shorter

Degree Program: Molecular, Cellular, and Developmental Biology
Email: shortekr@email.sc.edu
Room: CLS 605
Major Professor: Dr. Michael Felder

Research: Development of Peromyscus (deer mice) as a biomedical model is important as stocks maintained at the stock center are wild derived (not inbred as Mus and Rattus). My research centers around genetic and behavioral differences between two stocks, P. maniculatus and P. polionotus, and how genetics and epigenetics affect behaviors and various other phenotypes in these organisms, and how the effects are different between species. Projects include (1) development of the Peromyscus genetic map, (2) quantification and genetic analysis of behavioral differences between P. maniculatus and P. polionotus, (3) analysis of the pleiotropic effects of special diets in P. maniculatus and P. polionotus, and (4) determination of genetics and genetic mechanisms underlying growth retardation in P. maniculatus and P. polionotus hybrids (P. maniculatus female x P. polionotus male).

Education: B.S. Biology Converse College (2009), B.S. Chemistry Converse College (2009)

Grants and Fellowships:

(1) Kathryn Hinnant-Johnson Memorial Fellowship (2014)
(2) Jeffrey Barnesdale Teaching Assistant Award (2013)
(3) SPARC Grant from the VP for Research at the University of South Carolina (2013)

Teaching Assistantships:

(1) Chemistry 102-Introductory Chemistry Lab (2009-2010), University of South Carolina.
(2) Biology 545-Biochemistry Lab (2010), University of South Carolina.
(3) Biology 102-Introductory Biology Lab (2010-current), University of South Carolina.
(4) Biology 530-Histology Lab (2011-2013), University of South Carolina.

Meetings and Presentations:

(1) Poster: Genetic Background Influences Effects of a Methyl Donor Diet in Peromyscus." (2014). Keystone Symposium: Epigenetic Programming and Inheritance.

(2) Poster: "Pleiotropic Effects of a Methyl Diet." (2012) Society of Integrative and Comparative Biology.

(3) "Determination of the Effects of a Methyl Donor Diet in Peromyscus." (2011). Invited guest speaker for Science Forum at Converse College.

Publications:

Kimberly R. Shorter, Vanessa Anderson, Patricia Cakora, Keswick Lo, Denessia Webb, Janet P. Crossland, Michael R. Felder, and Paul B. Vrana. Pleitropic Effects of a Methyl Donor Diet in Peromyscus maniculatus. PLoS One (Accepted 3/26/14)

Kimberly R. Shorter, Amy Owen, Vanessa Anderson, April C. Hall-South, Samantha Hayford, Patricia Cakora, Janet P. Crossland, Velina R. M. Georgi, Amy Perkins, Sandra J. Kelly, Michael R. Felder, and Paul B. Vrana. 2014. Natural Genetic Variation Underlying Differences in Peromyscus Repetitive and Social/Aggressive Behaviors. Behavior Genetics DOI 10.1007/s10519-013-9640-8

Jane P. Kenney-Hunt, Adrienne Lewandowski, Travis C. Glenn, Julie L. Glenn, Olga V. Tsyusko, Rachel J. O’Neill, Judy Brown, Clifton M. Ramsdell, Quang Nguyen, Tony Phan, Kimberly R. Shorter, Michael J. Dewey, Gabor Szalai, Paul B. Vrana, and Michael R. Felder. 2013. A Peromyscus Genetic Map. Mammalian Genome DOI 10.1007/s00335-014-9500-8. *This article was on the cover with photo.

Paul B. Vrana, Kimberly R. Shorter, Gabor Szalai, Michael R. Felder, Janet P. Crossland, Monika Veres, Jasmine E. Allen, Christopher D. Wiley, Amanda R. Duselis, Michael J. Dewey and Wallace D. Dawson. 2013. Peromyscus (deer mice) as developmental models. WIREs Developmental Biology doi: 10.1002/wdev.132

Kimberly R. Shorter, Janet P. Crossland, Denessia Webb, Gabor Szalai, Michael R. Felder, and Paul B. Vrana. 2012. Peromyscus as a Mammalian Epigenetic Model. Genetics Research International
http://dx.doi.org/10.1155/2012/179159

Manuscripts in Preparation:

K.R. Shorter, S. Johnson, M.R. Felder, C. Rosenfeld, and P.B. Vrana. Genetic Background Influences Effects of a Methyl Donor Diet on Behavior in Peromyscus. Manuscript in preparation.

C.D Wiley, K.R. Shorter, J. Kenagy, and P.B. Vrana. Rapid evolution of Imprinting Control Regions & Implications for Peromyscus Phylogeny. Manuscript in preparation.

P.B. Vrana, K.R. Shorter, K. Dave, et. al. Genetics of Peromyscus Hybrid Post-Natal Growth. Manuscript in preparation.


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