Graduate Student Directory
Daniel T. Hughes
|Degree Program:||Molecular, Cellular, and Developmental Biology||Email:||email@example.com|
|Major Professor:||Marj Peña|
The focus of my research is to identify and understand the molecular mechanisms in the early stages of colorectal cancer metastasis. In our orthotopic mouse model, we have observed many genes to be upregulated in the liver prior to the arrival of tumor cells. Lipocalin 2, an iron trafficking protein, is highly upregulated in the pre-metastatic liver and is the most highly upregulated gene in a metastasis bearing liver.
This work is clinically relevant because colorectal cancer kills approximately 50,000 people in the United States annually, most of whom die from metastasis. Even with great research effort directed at understanding metastasis, it remains a complex multi-stage process that must be better understood to increase the extremely low survival rates for patients with metastatic cancer.
2011 B.S. Biology. North Greenville University. Tigerville, SC.
2007 Woodberry Forest School. Woodberry Forest, VA.
Graduate School Travel Grant. USC. 2014
SPARC Graduate Research Fellowship. USC. 2013
Associate Member, American Association for Cancer Research, January 2013 to present
Graduate Association for Biological Sciences, Fall 2012 to present
Preparing Future Faculty, Spring 2014 to present
Comparative Anatomy, Dept. of Biological Sciences. USC, Spring 2014, Spring 2017.
Biology 101, Dept. of Biological Sciences, USC, Fall 2013
Anatomy and Physiology I, Dept. of Exercise Science, USC, Fall 2011-Spring 2012