Soumitra Ghoshroy

Director, Electron Microscopy Center
Research Associate Professor, Biology
Ph. D. 1993, University of New Hampshire
803-777-7085
ghoshroy@mailbox.sc.edu

Electron Microscopy Center

Plant Cell Biology, Electron Microscopy, Plant-Virus Interaction.

My research interests lie in the area of plant cell structure, physiology, cellular and structural aspects of plant-virus interaction. I am currently using plant (tobacco and Arabidopsis) and turnip vein clearing virus (TVCV) interaction as a model system to study the mechanism of virus systemic movement process. In plants, the plasmodesmata are the intrercellular connections that play a major role in cell-cell communication. Many plant viruses can increase size exclusion limits of plasmodesmata to gain entry to the cells and eventually establish disease. In an infected leaf, virus first moves from cell-to-cell in mesophyll tissue and eventually to major and minor veins where the virus gains access to the phloem. It is critical for the virus to gain access to the veins to establish a systemic movement. It has already been shown that in Arabidopsis, TVCV enters the veins from mesophyll cells and then follows the assimilate flow from source to sink tissue resulting in systemic infection. We are currently using various microscopic tools to understand the mechanism of viral movement in plants that includes identifying host factor(s) involved in blockage of virus systemic movement. This information will help us to develop plants that are resistant to viral infection.

Selected Publications:

Lartey R.T. and Ghoshroy S. (2007) Association of selective deposition of (1’!3)-d"-glucan in floral tissues with restricted movement of turnip vein-clearing virus in Arabidopsis: A possible mechanism for non-seed transmission. Submitted.

Upadhyayula V. K. K., Ghoshroy S., Nair V. K., Smith G. B., Mitchell M. C., and Deng S. (2007) Carbon nanotubes-based sensors for pathogen detection. Submitted .

Lartey R.T., Kersey S., and Ghoshroy S. (2006) Comparative ultrastructural study of leaf spot infection of safflower and sugar beet by Cercospora beticola. Submitted.

Lartey R.T., Lenssen A.W., Evans R.G., and Ghoshroy S. (2007) Comparative structural study of leaf spot disease of safflower and sugar beet by Cercospora beticola. Plant Pathology J 6(1): 37-43.

Ortega1 J. L.,. Temple S. J., Bagga S., Ghoshroy S., and Sengupta-Gopalan C. (2004) Biochemical and molecular characterization of transgenic Lotus japonicus plants constitutively over-expressing a cytosolic glutamine synthetase gene. Planta 219(5): 807-818.

Bagga S., Armendaris A., Klypina N., Ray I., Ghoshroy S., Endress M., Sutton D., Kemp J. D., and Sengupta-Gopalan C. (2004) Genetic engineering ruminal stable high methionine protein in the foliage of alfalfa. Plant Science 166(2): 273-283.

Randall J., Sutton D., Ghoshroy S., Bagga S., and Kemp J. D. (2004) Co-ordinate expression of d" and ´ zeins in transgenic tobacco. Plant Science 167(2): 367-372.

Ghoshroy S. (2004) Characterization of plant viruses using microscopy techniques. In Emerging Concepts in Plant Health Management, ed. R.T. Lartey and A. Caesar. .

Waigmann, E., Chen, M.H., Bachmaier, R., Ghoshroy, S., & Citovsky, V. (2000) Regulation of plasmodesmal transport by phosphorylation of tobacco mosaic virus cell-to-cell movement protein. EMBO Journal 19: 4875-4884..

Ghoshroy S. and Citovsky V. (1998) Preservation of plant cell ultrastructure during immunolocalization of virus particles. Journal of Virological Methods 74: 223-229..

Citovsky V*, Ghoshroy S*. Tsui F., and Klessig D. (1998) Non-toxic concentrations of cadmium inhibit systemic movement of turnip vein clearing virus by a salicylic acid-independent mechanism. The Plant Journal 16(1): 13-20. *Equal contribution.

Ghoshroy S., Freedman K., Lartey R.T., and Citovsky V. (1998) Inhibition of plant viral systemic infection by non-toxic concentrations of cadmium. The Plant Journal 13(5): 591-602..

Sheng, J., Lartey, R., Ghoshroy, S., and Citovsky, V. (1998) An Arabidopsis thaliana mutant with virus-inducible phenotype. Virology 249(1):119-128..

Lartey R., Ghoshroy S., and Citovsky V. (1998) Identification of an Arabidopsis thaliana mutation (vsm1) that restricts systemic movement of tobamoviruses. Molecular Plant-Microbe Interaction 11(7): 706-709. .

Ghoshroy S. and Fagerberg W. R. (1998) Light detection in higher plant chloroplasts; pigment mediated or overall photon flux density related. International Journal of Plant Sciences 159: 110-115.

Lartey R. T., Ghoshroy S., Ho J., and Citovsky V. (1997) Movement and subcellular localization of a tobamovirus in Arabidopsis. The Plant Journal 12(3): 537-545..

Lartey R.T., Ghoshroy S., Sheng J., and Citovsky V. (1997) Transport through plasmodesmata and nuclear pores : cell-to-cell movement of plant viruses and nuclear import of Agrobacterium T-DNA. In Molecular Aspects of Host-Pathogen Interaction, ed. M.A. McCrae, J.R. Saunders, C.J..

Ghoshroy S., Lartey R.T., Sheng J., and Citovsky V. (1997) Transport of proteins and nucleic acids through plasmodesmata. Annual Review of Plant Physiology and Plant Molecular Biology 48: 27-50..

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